Deficiency of the seventh component of complement in an eight-year-old girl

Authors

  • A Werdani (1) University Hospital Thar Sfar of Mahdia, Pediatric Department, 5100 Mahdia, Tunisia ; (2) University Hospital La Rabta of Tunisia, immunology laboratory, 1007 Tunis, Tunisia Author
  • A Ben Mabrouk (1) University Hospital Thar Sfar of Mahdia, Pediatric Department, 5100 Mahdia, Tunisia ; (2) University Hospital La Rabta of Tunisia, immunology laboratory, 1007 Tunis, Tunisia Author
  • I Ayadi (1) University Hospital Thar Sfar of Mahdia, Pediatric Department, 5100 Mahdia, Tunisia ; (2) University Hospital La Rabta of Tunisia, immunology laboratory, 1007 Tunis, Tunisia Author
  • N Jemmali (1) University Hospital Thar Sfar of Mahdia, Pediatric Department, 5100 Mahdia, Tunisia ; (2) University Hospital La Rabta of Tunisia, immunology laboratory, 1007 Tunis, Tunisia Author
  • A Rassas (1) University Hospital Thar Sfar of Mahdia, Pediatric Department, 5100 Mahdia, Tunisia ; (2) University Hospital La Rabta of Tunisia, immunology laboratory, 1007 Tunis, Tunisia Author
  • M Kallel Sellami (1) University Hospital Thar Sfar of Mahdia, Pediatric Department, 5100 Mahdia, Tunisia ; (2) University Hospital La Rabta of Tunisia, immunology laboratory, 1007 Tunis, Tunisia Author
  • B Mahjoub (1) University Hospital Thar Sfar of Mahdia, Pediatric Department, 5100 Mahdia, Tunisia ; (2) University Hospital La Rabta of Tunisia, immunology laboratory, 1007 Tunis, Tunisia Author

Keywords:

Meningitis, Neisseria meningitidis, Complement component 7 deficiency

Abstract

Complement defects are uncommon. The late components of complement deficiency is associated with recurrent and invasive meningococcal infections especially meningitis. We report the case of an eight-year-old girl with no prior family or personal history of recurrent infections who was admitted twice in the paediatric department within four months for meningococcal meningitis. A complement system test revealed a seventh component of the complement deficiency.

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Published

2020-12-31

Issue

No. 20 (2020): October / December 2020

Section

Case Report

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