Chediak-Higashi syndrome: a new Tunisian case report

Authors

  • R Belhaj (1) Pediatric Dept, Hedi CHAKER University Hospital, Sfax ; (2) Hematology Laboratory, Hedi Chaker University Hospital, Sfax ; (3) Dept of Anatomopathology, Habib Bourguiba University Hospital, Sfax Author
  • I Chabchoub (1) Pediatric Dept, Hedi CHAKER University Hospital, Sfax ; (2) Hematology Laboratory, Hedi Chaker University Hospital, Sfax ; (3) Dept of Anatomopathology, Habib Bourguiba University Hospital, Sfax Author
  • H Charfi (1) Pediatric Dept, Hedi CHAKER University Hospital, Sfax ; (2) Hematology Laboratory, Hedi Chaker University Hospital, Sfax ; (3) Dept of Anatomopathology, Habib Bourguiba University Hospital, Sfax Author
  • M Chaari (1) Pediatric Dept, Hedi CHAKER University Hospital, Sfax ; (2) Hematology Laboratory, Hedi Chaker University Hospital, Sfax ; (3) Dept of Anatomopathology, Habib Bourguiba University Hospital, Sfax Author
  • L Ayadi (1) Pediatric Dept, Hedi CHAKER University Hospital, Sfax ; (2) Hematology Laboratory, Hedi Chaker University Hospital, Sfax ; (3) Dept of Anatomopathology, Habib Bourguiba University Hospital, Sfax Author
  • S Ben Ameur (1) Pediatric Dept, Hedi CHAKER University Hospital, Sfax ; (2) Hematology Laboratory, Hedi Chaker University Hospital, Sfax ; (3) Dept of Anatomopathology, Habib Bourguiba University Hospital, Sfax Author
  • Ch Kallel (1) Pediatric Dept, Hedi CHAKER University Hospital, Sfax ; (2) Hematology Laboratory, Hedi Chaker University Hospital, Sfax ; (3) Dept of Anatomopathology, Habib Bourguiba University Hospital, Sfax Author
  • T Boudaoura (1) Pediatric Dept, Hedi CHAKER University Hospital, Sfax ; (2) Hematology Laboratory, Hedi Chaker University Hospital, Sfax ; (3) Dept of Anatomopathology, Habib Bourguiba University Hospital, Sfax Author
  • Th Kammoun (1) Pediatric Dept, Hedi CHAKER University Hospital, Sfax ; (2) Hematology Laboratory, Hedi Chaker University Hospital, Sfax ; (3) Dept of Anatomopathology, Habib Bourguiba University Hospital, Sfax Author

Keywords:

Chediak-Higashi syndrome, Hemophagocytic lymphohistiocytosis, giant azurophilic granules, accelerated phase, syndrome de Chediak-Higashi, lymphohistiocytose hémophagocytaire, granules géants azurophiles, phase accélérée

Abstract

Chediak-Higashi syndrome (CHS) is a rare autosomal recessive congenital immunodeficiency characterized by the presence of giant azurophilic granules in granulocytes and other cells. We report the third Tunisian case in a 25-month-old boy presenting with accelerated phase.

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Published

2021-12-31

Issue

No. 24 (2021): October - December 2021

Section

Case Report

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