Cornelia de Lange syndrome about two cases

Abstract

Cornelia de Lange syndrome is a rare malformation syndrome, characterized by facial dysmorphism accompanied by intellectual deficit, significant growth retardation and extremity abnormalities and sometimes associated malformations (cardiac, kidney...). We report two cases that highlight this rare entity. Diagnosis is essentially done on the clinic. Prenatal diagnosis is possible by genetic study, but there is no curative treatment but psychoeducational care is essential.