Emergency Renal Replacement therapy in childhood

Abstract

Background : Acute kidney failure is a syndrome associated with a variety of diseases. It is a severe, life-threatening event. Objective : We aimed to describe patients' characteristics, indications for renal replacement therapy (RRT), and outcomes in children requiring emergency RRT. Patients and Methods : A retrospective cohort study of all patients with acute renal failure (ARF) receiving renal replacement therapy at the Pediatric Nephrology Unit in Charles Nicolle Hospital, Tunis from January 2012 to December 2017. Results : thirty children received RRT. The median age was 5±4.7 years. Hemolytic uremic syndrome (HUS) was diagnosed in 15 children (50%). Kidney recovery function (50%), chronic renal insufficiency (13%), end stage renal failure (27%) and death (10%) were the most evident. Conclusion : In patients with severe ARF, renal replacement therapy (RRT) represents a cornerstone of treatment, it can prevent complications and improve the prognosis.